Full name: ADP-ribosylation factor-like 6 interacting protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: AIP-6; ARMER; Aip-1; Arl6ip; mKIAA0069

Summary: Predicted to enable identical protein binding activity. Involved in positive regulation of L-glutamate import across plasma membrane. Acts upstream of or within cotranslational protein targeting to membrane. Located in cytosol and endoplasmic reticulum. Is integral component of membrane. Part of Sec61 translocon complex. Is expressed in several structures, including central nervous system; genitourinary system; retina; and stomach. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 61. Orthologous to human ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in placenta adult (RPKM 117.1), CNS E11.5 (RPKM 89.0) and 27 other tissues

Gene size: 10736bp

Exon count: 6