Full name: ADP ribosylation factor like GTPase 6 interacting protein 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AIP1; ARL6IP; ARMER; SPG61

Summary: This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Expression: Ubiquitous expression in brain (RPKM 151.5), adrenal (RPKM 96.4) and 25 other tissues

Gene size: 9883bp

Exon count: 7