Full name: paired related homeobox 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AGOTC; PHOX1; PMX1; PRX-1; PRX1

Summary: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]

Expression: Broad expression in endometrium (RPKM 34.6), fat (RPKM 27.9) and 17 other tissues

Gene size: 76654bp

Exon count: 6