Map3k14 mitogen-activated protein kinase kinase kinase 14 [ Mus musculus (house mouse) ] - Gene - Data resources

53859

Map3k14 mitogen-activated protein kinase kinase kinase 14 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 53859)

Symbol: Map3k14

Full name: mitogen-activated protein kinase kinase kinase 14

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Nik; aly

Summary: Enables NF-kappaB-inducing kinase activity. Involved in I-kappaB kinase/NF-kappaB signaling and immune response. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; sensory organ; and skeleton. Used to study Sjogren's syndrome and primary biliary cholangitis. Orthologous to human MAP3K14 (mitogen-activated protein kinase kinase kinase 14). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in spleen adult (RPKM 11.8), thymus adult (RPKM 8.3) and 23 other tissues

Orthologs: human

Gene size: 47638bp

Exon count: 16