PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Homo sapiens (human) ]
Source: NCBI Gene (ID 5293)
Source: NCBI Gene (ID 5293)
Symbol: PIK3CD
Full name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: APDS; IMD14; IMD14A; IMD14B; P110DELTA; PI3K; ROCHIS; p110D
Summary: Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]
Expression: Broad expression in lymph node (RPKM 21.4), bone marrow (RPKM 20.0) and 22 other tissues
Orthologs: mouse
Gene size: 101857bp
Exon count: 34