Full name: N-ribosyldihydronicotinamide:quinone reductase 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DHQV; DIA6; NMOR2; QR2

Summary: This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Expression: Broad expression in kidney (RPKM 43.3), fat (RPKM 18.6) and 24 other tissues

Gene size: 19862bp

Exon count: 10