Full name: N-ribosyldihydronicotinamide quinone reductase 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: NMO2; Nmor2; Ox2

Summary: Predicted to enable several functions, including anion binding activity; dihydronicotinamide riboside quinone reductase activity; and melatonin binding activity. Predicted to be involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron apoptotic process; and positive regulation of vascular associated smooth muscle cell proliferation. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in adenohypophysis. Human ortholog(s) of this gene implicated in Parkinson's disease; agranulocytosis; breast cancer; and breast carcinoma. Orthologous to human NQO2 (N-ribosyldihydronicotinamide:quinone reductase 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in liver adult (RPKM 9.5), placenta adult (RPKM 5.0) and 27 other tissues

Gene size: 23947bp

Exon count: 10