Nup85 nucleoporin 85 [ Mus musculus (house mouse) ] - Gene - Data resources

445007

Nup85 nucleoporin 85 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 445007)

Symbol: Nup85

Full name: nucleoporin 85

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Pcnt1; frount

Summary: Predicted to enable CCR2 chemokine receptor binding activity. Predicted to be a structural constituent of nuclear pore. Acts upstream of or within lamellipodium assembly and macrophage chemotaxis. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in several structures, including blastocyst; early embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in nephrotic syndrome type 17. Orthologous to human NUP85 (nucleoporin 85). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in liver E14.5 (RPKM 39.0), CNS E11.5 (RPKM 38.7) and 28 other tissues

Orthologs: human

Gene size: 19487bp

Exon count: 20