Tsen2 tRNA splicing endonuclease subunit 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 381802)
Source: NCBI Gene (ID 381802)
Symbol: Tsen2
Full name: tRNA splicing endonuclease subunit 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Summary: Predicted to enable tRNA-intron endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to act upstream of or within mRNA processing and tRNA processing. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of tRNA-intron endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2B. Orthologous to human TSEN2 (tRNA splicing endonuclease subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E18 (RPKM 6.3), CNS E14 (RPKM 5.4) and 28 other tissues
Orthologs: human
Gene size: 33725bp
Exon count: 12