IRS1 insulin receptor substrate 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 3667)
Source: NCBI Gene (ID 3667)
Symbol: IRS1
Full name: insulin receptor substrate 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: HIRS-1
Summary: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
Expression: Broad expression in thyroid (RPKM 15.0), endometrium (RPKM 12.3) and 22 other tissues
Orthologs: mouse
Gene size: 68509bp
Exon count: 4