Full name: interleukin 7 receptor

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CD127; CDW127; IL-7R-alpha; IL-7Ralpha; IL7RA; IL7Ralpha; ILRA; IMD104; lnc-IL7R; sIL-7R

Summary: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]

Expression: Biased expression in appendix (RPKM 75.5), lymph node (RPKM 68.1) and 10 other tissues

Gene size: 22713bp

Exon count: 8