Full name: interleukin 7 receptor

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: CD127; IL-7Ralpha

Summary: Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008]

Expression: Biased expression in spleen adult (RPKM 3.1), thymus adult (RPKM 2.6) and 8 other tissues

Gene size: 24391bp

Exon count: 10