Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 330953)
Source: NCBI Gene (ID 330953)
Symbol: Hcn4
Full name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Bcng3; Hcn3
Summary: Enables intracellular cAMP-activated cation channel activity. Acts upstream of or within cation transport; in utero embryonic development; and regulation of heart contraction. Located in axon. Is expressed in eye; future brain; heart; septum transversum; and venous system. Human ortholog(s) of this gene implicated in Brugada syndrome 8; Gilles de la Tourette syndrome; idiopathic generalized epilepsy; and sick sinus syndrome. Orthologous to human HCN4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in whole brain E14.5 (RPKM 4.8), CNS E14 (RPKM 3.6) and 17 other tissues
Orthologs: human
Gene size: 40227bp
Exon count: 8