Dock1 dedicator of cytokinesis 1 [ Mus musculus (house mouse) ] - Gene - Data resources

330662

Dock1 dedicator of cytokinesis 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 330662)

Symbol: Dock1

Full name: dedicator of cytokinesis 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 9130006G06Rik; D630004B07Rik; b2b3190Clo

Summary: Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Acts upstream of or within cell migration and hematopoietic progenitor cell differentiation. Predicted to be located in cytosol and nuclear speck. Predicted to be part of guanyl-nucleotide exchange factor complex. Is expressed in endocardial cushion and midgut vascular element. Used to study DiGeorge syndrome and tetralogy of Fallot. Orthologous to human DOCK1 (dedicator of cytokinesis 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in limb E14.5 (RPKM 10.8), adrenal adult (RPKM 9.5) and 28 other tissues

Orthologs: human

Gene size: 502961bp

Exon count: 52