NR4A1 nuclear receptor subfamily 4 group A member 1 [ Homo sapiens (human) ] - Gene - Data resources

3164

NR4A1 nuclear receptor subfamily 4 group A member 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 3164)

Symbol: NR4A1

Full name: nuclear receptor subfamily 4 group A member 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3

Summary: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Expression: Broad expression in adrenal (RPKM 103.3), ovary (RPKM 73.7) and 19 other tissues

Orthologs: mouse

Gene size: 36672bp

Exon count: 15