Full name: nuclear receptor subfamily 4, group A, member 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: GFRP1; Gfrp; Hbr-1; Hbr1; Hmr; N10; NGFI-B; NGFIB; NP10; NUR77-1; NUR77-2; TIS1; TR3; nur77

Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Involved in cellular response to corticotropin-releasing hormone stimulus; fat cell differentiation; and negative regulation of cell cycle. Acts upstream of or within several processes, including positive regulation of transcription by RNA polymerase II; regulation of apoptotic process; and skeletal muscle cell differentiation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including bone; genitourinary system; hemolymphoid system; nervous system; and submandibular gland primordium. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in adrenal adult (RPKM 65.6), thymus adult (RPKM 24.0) and 11 other tissues

Gene size: 20889bp

Exon count: 13