Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 26921)
Source: NCBI Gene (ID 26921)
Symbol: Map4k4
Full name: mitogen-activated protein kinase kinase kinase kinase 4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 9430080K19Rik; HGK; Nik
Summary: Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of cell-substrate junction organization; positive regulation of intracellular signal transduction; and positive regulation of keratinocyte migration. Located in focal adhesion. Is expressed in several structures, including genitourinary system; molar; nervous system; neural retina; and skin. Orthologous to human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E14 (RPKM 64.6), CNS E11.5 (RPKM 64.4) and 27 other tissues
Orthologs: human
Gene size: 125665bp
Exon count: 33