Robo2 roundabout guidance receptor 2 [ Mus musculus (house mouse) ] - Gene - Data resources

268902

Robo2 roundabout guidance receptor 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 268902)

Symbol: Robo2

Full name: roundabout guidance receptor 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2600013A04Rik; 9430089E08Rik; D230004I22Rik; mKIAA1568

Summary: Predicted to enable identical protein binding activity. Involved in several processes, including circulatory system development; neuron development; and positive regulation of Notch signaling pathway involved in heart induction. Acts upstream of or within axon guidance and metanephros development. Located in axolemma. Is expressed in several structures, including embryo mesenchyme; foot; jaw; nervous system; and urinary system. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human ROBO2 (roundabout guidance receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in CNS E18 (RPKM 11.3), whole brain E14.5 (RPKM 10.4) and 12 other tissues

Orthologs: human

Gene size: 1555468bp

Exon count: 34