Eme1 essential meiotic structure-specific endonuclease 1 [ Mus musculus (house mouse) ] - Gene - Data resources

268465

Eme1 essential meiotic structure-specific endonuclease 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 268465)

Symbol: Eme1

Full name: essential meiotic structure-specific endonuclease 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 6820428D13

Summary: Predicted to enable DNA binding activity; endonuclease activity; and metal ion binding activity. Predicted to be involved in DNA metabolic process and mitotic intra-S DNA damage checkpoint signaling. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Located in heterochromatin. Is expressed in several structures, including adrenal medulla; respiratory system; sensory organ; skeleton; and trunk mesenchyme derived from neural crest. Orthologous to human EME1 (essential meiotic structure-specific endonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in CNS E11.5 (RPKM 17.9), cortex adult (RPKM 15.1) and 26 other tissues

Orthologs: human

Gene size: 8814bp

Exon count: 10