Full name: GRB10 interacting GYF protein 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GYF2; PARK11; PERQ2; PERQ3; TNRC15

Summary: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Expression: Ubiquitous expression in testis (RPKM 16.1), thyroid (RPKM 9.2) and 25 other tissues

Gene size: 163275bp

Exon count: 35