Full name: GRB10 interacting GYF protein 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610016F01Rik; A830080H02Rik; Tnrc15; mKIAA0642

Summary: Predicted to enable proline-rich region binding activity. Acts upstream of or within several processes, including insulin-like growth factor receptor signaling pathway; mitotic G1 DNA damage checkpoint signaling; and spinal cord motor neuron differentiation. Located in several cellular components, including perikaryon; proximal dendrite; and vesicle. Is integral component of membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human GIGYF2 (GRB10 interacting GYF protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in placenta adult (RPKM 11.1), CNS E11.5 (RPKM 9.9) and 28 other tissues

Gene size: 123880bp

Exon count: 30