Sh2b2 SH2B adaptor protein 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 23921)
Source: NCBI Gene (ID 23921)
Symbol: Sh2b2
Full name: SH2B adaptor protein 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Aps
Summary: Enables transmembrane receptor protein tyrosine kinase adaptor activity. Involved in intracellular signal transduction. Acts upstream of or within several processes, including B-1 B cell homeostasis; brown fat cell differentiation; and cell surface receptor signaling pathway. Located in actin filament; ruffle; and stress fiber. Is expressed in dorsal aorta. Orthologous to human SH2B2 (SH2B adaptor protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in mammary gland adult (RPKM 32.6), adrenal adult (RPKM 26.0) and 14 other tissues
Orthologs: human
Gene size: 28451bp
Exon count: 11