Grem2 gremlin 2, DAN family BMP antagonist [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 23893)
Source: NCBI Gene (ID 23893)
Symbol: Grem2
Full name: gremlin 2, DAN family BMP antagonist
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Gremlin2; Prdc
Summary: Enables BMP binding activity; heparin binding activity; and identical protein binding activity. Involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including chondrocranium; integument; intestine smooth muscle circular layer; lung; and neural tube. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in ovary adult (RPKM 15.0), lung adult (RPKM 14.2) and 20 other tissues
Orthologs: human
Gene size: 88134bp
Exon count: 4