Full name: protein O-fucosyltransferase 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DDD2; FUT12; O-FUT; O-Fuc-T; O-FucT-1; OFUCT1

Summary: This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in thyroid (RPKM 10.9), small intestine (RPKM 10.7) and 25 other tissues

Gene size: 30779bp

Exon count: 9