Pofut1 protein O-fucosyltransferase 1 [ Mus musculus (house mouse) ] - Gene - Data resources

140484

Pofut1 protein O-fucosyltransferase 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 140484)

Symbol: Pofut1

Full name: protein O-fucosyltransferase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: O-FucT-1

Summary: Predicted to enable peptide-O-fucosyltransferase activity. Involved in Notch signaling pathway. Acts upstream of or within circulatory system development; nervous system development; and somitogenesis. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in brain; embryo; skeletal muscle tissue; and skeletal musculature. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in adrenal adult (RPKM 10.2), limb E14.5 (RPKM 10.0) and 28 other tissues

Orthologs: human

Gene size: 29498bp

Exon count: 8