Arhgap35 Rho GTPase activating protein 35 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 232906)
Source: NCBI Gene (ID 232906)
Symbol: Arhgap35
Full name: Rho GTPase activating protein 35
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 6430596G11Rik; Grlf1; mKIAA1722; p190A; p190RhoGAP
Summary: Enables GTPase activator activity. Involved in several processes, including axon development; establishment or maintenance of actin cytoskeleton polarity; and regulation of plasma membrane bounded cell projection organization. Acts upstream of or within several processes, including negative regulation of Rho protein signal transduction; negative regulation of vascular permeability; and nervous system development. Located in actin cytoskeleton; ciliary basal body; and cytoplasm. Is expressed in central nervous system and eye. Orthologous to human ARHGAP35 (Rho GTPase activating protein 35). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in whole brain E14.5 (RPKM 20.1), ovary adult (RPKM 18.9) and 28 other tissues
Orthologs: human
Gene size: 120916bp
Exon count: 9