PLCB1 phospholipase C beta 1 [ Homo sapiens (human) ] - Gene - Data resources

23236

PLCB1 phospholipase C beta 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 23236)

Symbol: PLCB1

Full name: phospholipase C beta 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DEE12; EIEE12; PI-PLC; PLC-154; PLC-I; PLC-beta-1; PLC154; PLCB1A; PLCB1B

Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Expression: Broad expression in brain (RPKM 18.8), salivary gland (RPKM 3.8) and 17 other tissues

Orthologs: mouse

Gene size: 752635bp

Exon count: 33