SYNE2 spectrin repeat containing nuclear envelope protein 2 [ Homo sapiens (human) ] - Gene - Data resources

23224

SYNE2 spectrin repeat containing nuclear envelope protein 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 23224)

Symbol: SYNE2

Full name: spectrin repeat containing nuclear envelope protein 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: EDMD5; KASH2; NUA; NUANCE; Nesp2; Nesprin-2; SYNE-2; TROPH

Summary: The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Expression: Ubiquitous expression in skin (RPKM 13.7), kidney (RPKM 12.6) and 25 other tissues

Orthologs: mouse

Gene size: 464854bp

Exon count: 125