Syne2 spectrin repeat containing, nuclear envelope 2 [ Mus musculus (house mouse) ] - Gene - Data resources

319565

Syne2 spectrin repeat containing, nuclear envelope 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 319565)

Symbol: Syne2

Full name: spectrin repeat containing, nuclear envelope 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 6820443O06Rik; Cpfl8; D12Ertd777e; KASH2; NUA; Nesp2g; dice; mKIAA1011

Summary: Enables actin binding activity. Involved in several processes, including centrosome localization; nuclear migration; and regulation of cilium assembly. Acts upstream of or within several processes, including fibroblast migration; nuclear envelope organization; and protein localization to nucleus. Located in Z disc and nuclear outer membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 5. Orthologous to human SYNE2 (spectrin repeat containing nuclear envelope protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in ovary adult (RPKM 15.6), genital fat pad adult (RPKM 6.8) and 25 other tissues

Orthologs: human

Gene size: 292611bp

Exon count: 116