ERC1 ELKS/RAB6-interacting/CAST family member 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 23085)
Source: NCBI Gene (ID 23085)
Symbol: ERC1
Full name: ELKS/RAB6-interacting/CAST family member 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: Cast2; ELKS; ERC-1; RAB6IP2
Summary: The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Expression: Ubiquitous expression in thyroid (RPKM 7.0), esophagus (RPKM 6.1) and 25 other tissues
Orthologs: mouse
Gene size: 505975bp
Exon count: 28