Erc1 ELKS/RAB6-interacting/CAST family member 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 111173)
Source: NCBI Gene (ID 111173)
Symbol: Erc1
Full name: ELKS/RAB6-interacting/CAST family member 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST2; ELKS; Elks1; RAB6IP2A; RAB6IP2B; Rab6ip2; mKIAA1081
Summary: Enables small GTPase binding activity and voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels. A structural constituent of presynaptic active zone. Involved in synaptic vesicle priming. Acts upstream of or within retrograde transport, endosome to Golgi. Located in GABA-ergic synapse; cytoplasm; and glutamatergic synapse. Is expressed in several structures, including genitourinary system; gut gland; oral epithelium; retina; and telencephalon. Orthologous to human ERC1 (ELKS/RAB6-interacting/CAST family member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E18 (RPKM 12.2), whole brain E14.5 (RPKM 10.4) and 28 other tissues
Orthologs: human
Gene size: 283229bp
Exon count: 24