FANCC FA complementation group C [ Homo sapiens (human) ] - Gene - Data resources

2176

FANCC FA complementation group C [ Homo sapiens (human) ]
Source: NCBI Gene (ID 2176)

Symbol: FANCC

Full name: FA complementation group C

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FA3; FAC; FACC

Summary: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]

Expression: Broad expression in testis (RPKM 3.8), liver (RPKM 2.1) and 24 other tissues

Orthologs: mouse

Gene size: 218656bp

Exon count: 25