Fancc Fanconi anemia, complementation group C [ Mus musculus (house mouse) ] - Gene - Data resources

14088

Fancc Fanconi anemia, complementation group C [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 14088)

Symbol: Fancc

Full name: Fanconi anemia, complementation group C

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Facc

Summary: Acts upstream of or within several processes, including brain morphogenesis; neuronal stem cell population maintenance; and removal of superoxide radicals. Predicted to be located in chromatin and cytosol. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; reproductive system; retina nuclear layer; and skeleton. Used to study Fanconi anemia complementation group C. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple); acute myeloid leukemia; aspirin-induced respiratory disease; pancreatic cancer; and pancytopenia. Orthologous to human FANCC (FA complementation group C). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in bladder adult (RPKM 3.8), CNS E11.5 (RPKM 3.0) and 28 other tissues

Orthologs: human

Gene size: 192608bp

Exon count: 22