Lzts1 leucine zipper, putative tumor suppressor 1 [ Mus musculus (house mouse) ] - Gene - Data resources

211134

Lzts1 leucine zipper, putative tumor suppressor 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 211134)

Symbol: Lzts1

Full name: leucine zipper, putative tumor suppressor 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: F37; FEZ1; PSD-Zip70

Summary: Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of macroautophagy; regulation of dendrite morphogenesis; and regulation of synaptic plasticity. Predicted to be located in several cellular components, including apical plasma membrane; dendritic shaft; and postsynaptic density. Predicted to be active in dendritic spine. Is expressed in several structures, including brain and metanephros. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in frontal lobe adult (RPKM 14.3), cortex adult (RPKM 13.3) and 14 other tissues

Orthologs: human

Gene size: 51591bp

Exon count: 7