Spint2 serine protease inhibitor, Kunitz type 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20733)
Symbol: Spint2
Full name: serine protease inhibitor, Kunitz type 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: HAI-2
Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within basement membrane organization; chordate embryonic development; and establishment or maintenance of cell polarity. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 3. Orthologous to human SPINT2 (serine peptidase inhibitor, Kunitz type 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in colon adult (RPKM 448.1), duodenum adult (RPKM 435.7) and 13 other tissues
Orthologs: human
Gene size: 25730bp
Exon count: 8