Full name: secreted frizzled-related protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2210415K03Rik; sFRP-1

Summary: Predicted to enable several functions, including Wnt-protein binding activity; frizzled binding activity; and heparin binding activity. Involved in several processes, including cellular response to X-ray; cellular response to estrogen stimulus; and negative regulation of B cell differentiation. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SFRP1 (secreted frizzled related protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in kidney adult (RPKM 23.7), CNS E11.5 (RPKM 22.8) and 26 other tissues

Gene size: 38248bp

Exon count: 4