Rspo1 R-spondin 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 192199)
Source: NCBI Gene (ID 192199)
Symbol: Rspo1
Full name: R-spondin 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: R-spondin; Rspondin
Summary: Enables heparin binding activity and signaling receptor binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including male meiotic nuclear division; positive regulation of non-canonical Wnt signaling pathway; and regulation of male germ cell proliferation. Located in extracellular space and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and skeleton. Orthologous to human RSPO1 (R-spondin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in ovary adult (RPKM 13.8), CNS E11.5 (RPKM 10.5) and 19 other tissues
Orthologs: human
Gene size: 22699bp
Exon count: 6