Full name: lysophosphatidic acid receptor 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: EDG2; Gpcr26; LPA1; Mrec1.3; VZG1; edg-2; rec.1.3; vzg-1

Summary: The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020]

Expression: Ubiquitous expression in brain (RPKM 14.7), placenta (RPKM 8.1) and 22 other tissues

Gene size: 165736bp

Exon count: 16