Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 18816)
Source: NCBI Gene (ID 18816)
Symbol: Serpinf2
Full name: serine (or cysteine) peptidase inhibitor, clade F, member 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Pli; Serpimf2
Summary: Predicted to enable protease binding activity; protein homodimerization activity; and serine-type endopeptidase inhibitor activity. Involved in several processes, including collagen fibril organization; maintenance of blood vessel diameter homeostasis by renin-angiotensin; and positive regulation of biosynthetic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including liver; pancreas epithelium; urinary system; and yolk sac. Used to study alpha-2-plasmin inhibitor deficiency. Human ortholog(s) of this gene implicated in COVID-19 and alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (serpin family F member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver adult (RPKM 505.8), liver E18 (RPKM 427.0) and 5 other tissues
Orthologs: human
Gene size: 7766bp
Exon count: 10