Pld3 phospholipase D family, member 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 18807)
Source: NCBI Gene (ID 18807)
Symbol: Pld3
Full name: phospholipase D family, member 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Sam-9
Summary: Enables single-stranded DNA 5'-3' exodeoxyribonuclease activity. Involved in regulation of cytokine production involved in inflammatory response. Located in late endosome membrane and lysosomal membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Orthologous to human PLD3 (phospholipase D family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in cortex adult (RPKM 194.3), frontal lobe adult (RPKM 152.9) and 28 other tissues
Orthologs: human
Gene size: 21821bp
Exon count: 15