Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 18018)
Source: NCBI Gene (ID 18018)
Symbol: Nfatc1
Full name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2210017P03Rik; NF-ATc; NFAT2; NFATc; Nfatcb
Summary: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and mitogen-activated protein kinase p38 binding activity. Involved in heart development and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; branching involved in lymph vessel morphogenesis; and regulation of gene expression. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; eye; genitourinary system; and heart. Orthologous to human NFATC1 (nuclear factor of activated T cells 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in spleen adult (RPKM 23.0), thymus adult (RPKM 14.6) and 15 other tissues
Orthologs: human
Gene size: 106869bp
Exon count: 13