Full name: H1.8 linker histone

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: H1-8; H1.8; H1fo; H1foo; H1oo

Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes and the encoded protein is expressed only in oocytes. [provided by RefSeq, Oct 2015]

Expression: Restricted expression toward ovary adult (RPKM 8.4)

Gene size: 5312bp

Exon count: 5