H1-8 H1.8 linker histone [ Homo sapiens (human) ]
Source: NCBI Gene (ID 132243)
Symbol: H1-8
Full name: H1.8 linker histone
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: H1.8; H1FOO; H1oo; osH1
Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Oct 2015]
Expression: Low expression observed in reference dataset
Orthologs: mouse
Gene size: 8293bp
Exon count: 6