Itpr3 inositol 1,4,5-triphosphate receptor 3 [ Mus musculus (house mouse) ] - Gene - Data resources

16440

Itpr3 inositol 1,4,5-triphosphate receptor 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 16440)

Symbol: Itpr3

Full name: inositol 1,4,5-triphosphate receptor 3

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: IP3R 3; Ip3r3; Itpr-3; tf

Summary: Enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity and phosphatidylinositol binding activity. Involved in calcium ion transport into cytosol. Acts upstream of or within several processes, including long-term synaptic potentiation; memory; and sensory perception of taste. Located in endoplasmic reticulum membrane; nucleolus; and nucleoplasm. Is expressed in several structures, including jaw; liver; sensory organ; skeleton; and spleen. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ITPR3 (inositol 1,4,5-trisphosphate receptor type 3). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in stomach adult (RPKM 33.0), spleen adult (RPKM 27.9) and 17 other tissues

Orthologs: human

Gene size: 65222bp

Exon count: 58