Full name: cathepsin E

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CATE

Summary: This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. [provided by RefSeq, Nov 2015]

Expression: Biased expression in stomach (RPKM 543.0) and duodenum (RPKM 112.5)

Gene size: 14632bp

Exon count: 9