Full name: C-terminal binding protein 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BARS; HADDTS

Summary: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in spleen (RPKM 9.3), prostate (RPKM 7.1) and 25 other tissues

Gene size: 38911bp

Exon count: 14