Ctbp1 C-terminal binding protein 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13016)
Symbol: Ctbp1
Full name: C-terminal binding protein 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: BARS; CtBP3/BARS; D4S115h; D5H4S115; D5H4S115E
Summary: Enables chromatin binding activity. Involved in negative regulation of transcription, DNA-templated and white fat cell differentiation. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription repressor complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Is expressed in several structures, including central nervous system; genitourinary system; limb; lung; and neural retina. Orthologous to human CTBP1 (C-terminal binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in ovary adult (RPKM 109.8), CNS E14 (RPKM 100.4) and 28 other tissues
Orthologs: human
Gene size: 27401bp
Exon count: 10