Full name: drosha, ribonuclease type III

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1110013A17Rik; Etohi2; Rn3; Rnasen

Summary: Enables endoribonuclease activity and primary miRNA binding activity. Involved in positive regulation of gene expression. Acts upstream of or within several processes, including ncRNA metabolic process; regulation of miRNA metabolic process; and regulation of regulatory T cell differentiation. Located in postsynaptic density. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; hemolymphoid system gland; and tooth. Orthologous to human DROSHA (drosha ribonuclease III). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 18.2), CNS E14 (RPKM 14.7) and 27 other tissues

Gene size: 110485bp

Exon count: 36