Full name: epoxide hydrolase 1, microsomal

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: EH; Eph-1; Eph1; Epxh1; mEH

Summary: Predicted to enable cis-stilbene-oxide hydrolase activity; enzyme binding activity; and epoxide hydrolase activity. Acts upstream of or within cellular aromatic compound metabolic process and response to organic cyclic compound. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Is expressed in several structures, including brain ventricle and choroid plexus; cranial ganglion; integumental system; nose; and salivary gland. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver adult (RPKM 113.7), bladder adult (RPKM 62.6) and 19 other tissues

Gene size: 28014bp

Exon count: 9