Dlk1 delta like non-canonical Notch ligand 1 [ Mus musculus (house mouse) ] - Gene - Data resources

13386

Dlk1 delta like non-canonical Notch ligand 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13386)

Symbol: Dlk1

Full name: delta like non-canonical Notch ligand 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: DLK-1; DlkI; FA1; Ly107; Peg9; SCP1; ZOG; pG2; pref-1

Summary: Predicted to enable calcium ion binding activity. Involved in negative regulation of fat cell differentiation and negative regulation of vascular endothelial cell proliferation. Acts upstream of or within several processes, including bone mineralization; negative regulation of Notch signaling pathway; and positive regulation of bone resorption. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; embryo mesenchyme; genitourinary system; and nervous system. Orthologous to human DLK1 (delta like non-canonical Notch ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in limb E14.5 (RPKM 294.1), liver E14.5 (RPKM 215.8) and 7 other tissues

Orthologs: human

Gene size: 10852bp

Exon count: 8